Intra Uterine Insemination (IUI)
IUI is the process of placing processed semen sample containing motile sperms through the cervix into the uterine cavity around the time of ovulation.
Who Does IUI Treatment Help?
IUI is generally the first line of treatment when medication and timed intercourse does not succeed. It is recommended for patients with mild to moderate decrease in sperm count and/or motility, or if there is mild endometriosis. For women who do not ovulate regularly, ovulation induction maybe combined with IUI. Also, for some couples who don’t have any apparent cause for infertility (unexplained infertility), IUI may be advised.
What Are The Requirements Before IUI Procedure?
- Confirmation that you are ovulating, either with or without medications
- Patent tubes
- A normal or mild to moderately decreased sperm count
Treatment
You will generally be advised medications (oral tablets and / or gonadotropin injections) from day 2 or 3 of your menses for 5-10 days. Your response will be monitored by sonography every 3-4 days.
When the follicle/s are of appropriate size, the final process of ovulation will be triggered with an injection of hCG and the IUI procedure will be planned approximately 36 hours later.
Your partner needs to provide his semen sample on the day of an IUI. If a problem is anticipated, previously preserved sample can also be used. The semen sample is processed in the laboratory and then injected into the uterus.
You may then be given medications for support for the next 14 days at the end of which a serum beta-hCG test is done to confirm pregnancy.
Precautions
Since this is a relatively simple and safe procedure, it does not require any special precautions. Only a few minutes rest after the procedure and then you can resume your routine.
Possible complications
Apart from mild pain and spotting on the day of an IUI, there are no major complications. Around five to ten percent of the patients have multiple (generally twin) pregnancies. Sometimes, a patient may respond excessively to medications and produce more eggs, putting her at risk for multiple pregnancies and a condition called Ovarian Hyper Stimulation Syndrome (OHSS). If there is a risk of this occurring, your doctor will advise you accordingly and the cycle may be cancelled or converted to an IVF cycle. Infection is a very rare complication.
Frequently Asked Questions
IVF was originally developed for women with blocked tubes or missing fallopian tubes and it is still the procedure of choice for these situations. It is also used when other conditions are present, including endometriosis, male factor infertility and unexplained infertility in which no medical cause for infertility can be found. Our experts will review your history and help to guide you to the treatment and diagnostic procedures that are most appropriate for you.
1/3rd of the infertility issues are contributed by the male partner. Male factors also influence increased rate of miscarriages. Most common causes of male infertility are as follows.
Abnormal sperm count or low sperm motility
Chronic ailments such as cancer
Environmental factors: Exposure to radioactive chemicals
Lifestyle factors: Being overweight, smoking, drinking alcohol
Age
Infertility is gender neutral. It affects the male and the female population. 1/3rd of the infertility issues are contributed by the female partner. In the world 50-80 million suffer from infertility. Most common causes of female infertility are as follows.
Age
Endometriosis
Hormonal issues leading to ovulation problems
Tubal blockage
Fibroids
Lifestyle factors: Being overweight, smoking, drinking alcohol, unhealthy diet
Unexplained infertility
Increased age can lead to decreased oravian reserve which can in turn affect the number of oocytes retrieved. Also increased age is in inversely proportional to the quality of oocytes.
PCOS patients might not form any eggs even after taking medicines or may require high dosage of gonadotrophins which may in turn give rise to many oocytes forming together, follicle rupture becomes an issue with these kind of patients IVF can help in such cases.

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